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See papers in SpringerPlus 2015, BMC Nephrology 2015, Environmental Health 2015, International Journal of Environmental Research and Public Health 2014. The AAAS award had been suspended amidst a fierce opposition campaign by pesticide industry allies to undermine the work of the scientists. After a review, the AAAS reinstated the award. Some farmers use glyphosate on non GMO crops such as wheat, barley, oats, and lentils to dry down the crop ahead of harvest in order to accelerate the harvest. This practice, known as desiccation, may be a significant source of dietary exposure to glyphosate. The USDA quietly dropped a plan to start testing food for residues of glyphosate in 2017.


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Scientists found that the compound piceatannol, found naturally in the skin of grapes and other fruits blocks an immature fat cells ability to develop and grow, opening a door to a potential method to control obesity. The lead study author, Dr. Kee Hong Kim found that piceatannol, an analog of resveratrol found in grapes and other fruit, is converted to piceatannol in humans following its consumption. The team tested piceatannol in cultured immature fat cells called preadipocytes to determine if the compound inhibited the maturity process that results in fully developed fat cells, capable of storing body fat and contributing to obesity. Dr. Kim commented We consider that adipogenesis is an important molecular target to delay or prevent fat cell accumulation and, hopefully, body fat mass gain. The team found that piceatannol bound to the insulin receptor on the immature fat cells, effectively blocking insulins ability to control normal cellular cycling resulting in mature adipocytes. The grape derived compound stimulated the activation of special genes necessary for the fat cell maturation process. The study authors concluded Piceatannol actually alters the timing of gene expressions, gene functions and insulin action during adipogenesis, the process in which early stage fat cells become mature fat cells in the presence of piceatannol, you can see delay or complete inhibition of adipogenesis. Similar in structure to resveratrol, scientists believe piceatannol may also exert some of the same properties to help combat cancer, heart disease and neurodegenerative conditions. Piceatannol is yet another natural compound that has demonstrated the ability to influence genetic expression to inhibit the formation of adipocytes or alter metabolism to help achieve weight management goals alongside resveratrol, green tea catechins EGCG and irvingia gabonensis.



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